run n up against意外地碰到;意外地碰到困难
run up against Ass遇到
run up against the matter摊上一桩麻烦事儿
PHRASAL VERB（动词词组） If you run up against problems, you suddenly begin to experience them. 遇到
I ran up against the problem of getting taken seriously long before I became a writer.
还远没有成为作家我就碰到了得到重视的问题。